His style combined the technical precision of the Netherlandish tradition with the Renaissance interest in individual character. In works such as Portrait of a Man and Portrait of a Woman, he used dark backgrounds to direct attention toward the face and hands of the subject. He rendered textures like fur and velvet alongside gold jewellery. Modern X-ray analysis of his Coronation of the Virgin Altarpiece shows how he planned these compositions using detailed underdrawings. These scans reveal a disciplined method of construction.

Collectors value Bruyn for his ability to convey status through subtle visual cues. His portraits, such as the one traditionally identified as Roger, Count Blitterswyk-Geldern, provide a window into 16th-century fashion and social hierarchy. The clear lines and balanced compositions of his work suit contemporary interiors. His paintings offer a sense of calm and historical continuity. The focus on the human subject makes these pieces approachable for those interested in the history of Northern European portraiture.