His work focuses on precise linework and mythological subjects. Picart moved away from the heavy styles of the previous century. He preferred clarity and proportion in his compositions. His etchings, such as "Althaea Putting the Fatal Log on the Fire" or his studies of antique gems, show a controlled hand. He often used vignettes and ornaments, including skulls and griffins, to frame larger narratives or to stand as independent decorative elements.

Modern collectors value Picart for his balance of classical themes and clean graphic sensibility. His prints work well in contemporary spaces because they offer historical depth without visual clutter. The monochrome compositions provide a sharp contrast for minimalist or traditional interiors. His focus on symbolic ornaments like the two-headed eagle or Mercury makes his work feel like a curated collection of curiosities for the home.