His work is defined by a heavy use of light and a specific realism. He belonged to the Brescian school, where artists favoured silver tones and direct observation. Romanino often depicted figures with a sense of physical weight. His Saint Catherine of Alexandria shows this interest in tactile fabrics and human expression. He did not aim for idealised beauty. Instead, he painted with a rougher hand that captured physical textures.

Modern collectors value Romanino for his independent spirit and bold compositions. His prints bring a sense of history into a room without feeling overly formal. The sketches of Romulus and Remus or the Concentric Circles show his technical skill. These works offer a window into the mind of a painter who resisted standard trends. His art balances classical subjects with a raw, honest execution.